ATTENTION PORT-WINE BIRTHMARKS AND/OR STURGE-WEBER SYNDROME PATIENTS 

The Department of Dermatology at the University of California, Irvine is conducting a research study evaluating the cause of Port-Wine Birthmarks and Sturge-Weber Syndrome. 

Study Title: Role of Angiogenesis in Cutaneous Disease: A Potential Therapeutic Target 

Lead Researcher: Kristen Kelly, M.D. 

Project details: This project aims to study how new blood vessels grow in skin diseases. We hope to use this information to develop new treatments. 

For example, Sturge-Weber Syndrome is an acquired mutation in the GNAQ gene. It has been hypothesized that additional mutations occur in the tissue and could explain changes in the birthmark. We hope to identify these changes which may give us an idea on potential new treatments. 

We need research participants who: 
• Are 18 years or older
• Are diagnosed with Sturge-Weber Syndrome.
• Are willing to have one or more small (pencil eraser size) biopsies taken of your skin.

If you decide to be in this study and the study doctor says you can be in the study: 
• You will have biopsies taken.
• You will not be compensated for your participation in this research study.

Qualified research participants will receive: 
• Examination of birthmark by Dr. Kristen Kelly.

–If you are interested, please call today to find out more –
Julia Terrell, Director of Community Relations, The Sturge-Weber Foundation 
Office number: (973) 895-4445 x802 • Cell phone: (609) 425-0313